Leveraging the science of buffering increases the predictability and speed at which a patient can get numb. This, in turn, creates a better patient experience and increases the efficiency of the practitioner. Through buffering, the doctor can remain chairside to get most patients profoundly numb in as little as 2 minutes. The closed mixing system offers extreme patient safety in the delivery and buffering of local anesthetic. Via patented, filtered, uniflow, and sterile-path technology, the cassette is able to maintain the vial’s sterility for up to 7 days.