Self-sealing sterilization pouches for sterilization with autoclaves and ethylene oxide (EtO) chambers. Dual (internal and external) process steam indicators will change color when a sterilization process has begun (steam/EtO). To confirm sterilization, use a biological monitor. Leak-resistant. Maintains sterilization for up to 12 months (once sterile and items remain sealed in the pouch). Made with medical-grade paper and an easy-to-open thumb notch. When used properly, it assists with CDC infection control guidelines compliance.