Uses a powerful combination of arginine and calcium carbonate, both derived from natural sources, to seal the pathways to sensitive tooth nerves to help block the pain. Clinically proven formula provides relief in 60 seconds and long-lasting protection with continuous use. No artificial dyes, sweeteners, or preservatives. Fluoride- and gluten-free. Recyclable tube with blue recycling flag: after all toothpaste is squeezed out, replace the cap and recycle. Fresh flavor.